CRP or the C reactive protein is a protein which is made by the liver in response to inflammation anywhere in the body. Hs-CRP is more sensitive than the CRP and can detect lower levels of this protein in the blood. High Hs-CRP levels indicate a risk of getting coronary heart disease. Also, in people who have had a cardiac event, if the Hs-CRP is high, they have higher chances of having a heart attack. If the Hs-CRP levels are normal, the likelihood of another cardiac event is low. Hs-CRP can also be increased in other inflammatory conditions and does not tell the cause of the inflammations. Hs-CRP has to be interpreted with other investigations and clinical features and lifestyle patterns